Projects

OPPORTUNITYThe biology separating a contained bladder tumor from one that invades is unresolved, yet that single distinction drives entirely different treatment paths.

WHAT I BUILTA four-stage R pipeline — differential expression, functional enrichment, immune deconvolution, and longitudinal visualization — tracing molecular and immune change from pre-cancer to muscle-invasive disease.

IMPACTSurfaced an EMT/ECM remodeling signature at tumor onset and a TNF-driven inflammatory shift at invasion, plus immune-composition changes relevant to immunotherapy timing and patient selection.

OPPORTUNITYConsumers receive dense genetic and health data they can't interpret or act on.

WHAT WE BUILTA consumer health product concept that translates genomic results into clear, prioritized, actionable guidance — built as a team.

IMPACTEnd-to-end product and UX design connecting complex genomics to everyday health decisions.

OPPORTUNITYAlzheimer's affects millions but has no confirmed cause or disease-modifying treatment; gene expression from post-mortem brain tissue could reveal biomarkers for staging or targets.

WHAT WE BUILTA differential expression and multi-database pathway enrichment pipeline in R, comparing moderate vs. incipient and severe vs. moderate AD stages, with literature-grounded interpretation of four candidate pathways.

IMPACTIdentified four biologically coherent themes — estrogen signaling loss, insulin resistance, neuroinflammation, and mitochondrial dysfunction — that track with disease severity and are supported by primary literature.

OPPORTUNITYReal-world evidence lives in fragmented, poorly documented datasets, making discovery slow and quality hard to trust.

WHAT I BUILTA full-stack platform for ICA.ai that unifies RWE datasets behind AI-powered discovery, automated FAIR quality scoring, and real-time team collaboration.

IMPACTCut data discovery time by 75% while making dataset quality visible and comparable across teams.

OPPORTUNITYSmoking status is buried in free-text discharge notes, making it costly to extract for research cohort building, quality reporting, and risk stratification.

WHAT I BUILTA complete clinical NLP pipeline from raw XML to a fine-tuned transformer, combining bag-of-words features, domain-specific keyword injection, ADASYN rebalancing, grid-searched classical ML, and ClinicalBERT fine-tuning.

IMPACTA methodologically sound end-to-end pipeline that correctly diagnoses severe class imbalance as the central failure mode rather than inflating accuracy.

OPPORTUNITYDoor-to-balloon delays in STEMI care directly worsen mortality, yet the workflow was reactive and manual — a classic emergency cardiology quality problem.

WHAT I BUILTA full QI cycle: SQL cohort construction from a synthetic EHR, three live OpenEMR clinical decision support rules, and a multi-angle evaluation covering cost, workflow timing, and staff sentiment.

IMPACTDemonstrated a functioning alert-driven intervention with honest adoption findings (ease-of-learning gap) that directly shaped an incremental rollout recommendation.

OPPORTUNITYStress is continuous and physiological, but most interventions are manual and arrive far too late.

WHAT I BUILTAn ML pipeline that classifies stress from wearable sensor signals and integrates with Spotify to trigger calming, adaptive playlists.

IMPACTA closed-loop wellness prototype that senses stress and responds in the moment with music therapy.